doi: 10.1089/hyb.1987.6.77.
Development and characterization of monoclonal antibodies to bovine brain calcineurin
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- PMID: 2445654
- DOI: 10.1089/hyb.1987.6.77
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Development and characterization of monoclonal antibodies to bovine brain calcineurin
Hybridoma.
1987 Feb.
Abstract
Three monoclonal antibodies (MAb's) against bovine brain calcineurin, a Ca++-calmodulin dependent phosphatase, have been developed and characterized. Among these antibodies, two are alpha-subunit (60,000 Mr) specific and one is beta-subunit (19,000 Mr) specific. These antibodies also cross-react with similar proteins obtained from brains of human, rat and mouse. The methodology for raising these antibodies and their properties are described.
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