Comment on

• IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV.

  Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC. Monroe KM, et al. Science. 2014 Jan 24;343(6169):428-32. doi: 10.1126/science.1243640. Epub 2013 Dec 19. Science. 2014. PMID: 24356113 Free PMC article.
• Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.

  Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. Doitsh G, et al. Nature. 2014 Jan 23;505(7484):509-14. doi: 10.1038/nature12940. Nature. 2014. PMID: 24356306 Free PMC article.