doi: 10.1016/0022-2836(87)90617-6.
DNA-binding fingers encoded by a trypanosome retroposon
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- PMID: 2445994
- DOI: 10.1016/0022-2836(87)90617-6
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DNA-binding fingers encoded by a trypanosome retroposon
J Mol Biol.
.
Abstract
A Trypanosoma brucei repeated DNA element (TRS-1, for trypanosome repeated sequence), which seems transposable, may encode a 1651 amino acid polypeptide showing homology with reverse transcriptase. This polypeptide would also carry a DNA-binding domain, as suggested by the presence of five DNA-binding "fingers" homologous to those of the transcription factor TFIIIA of Xenopus laevis and retroviral DNA-binding proteins.
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