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Comment
. 2014 Feb;63(2):381-3.
doi: 10.2337/db13-1586.

Irisin ERKs the fat

Jun Wu  1 , Bruce M Spiegelman
Affiliations
Comment

Irisin ERKs the fat

Jun Wu et al. Diabetes. 2014 Feb.
No abstract available

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Figures

Figure 1
Figure 1
Recombinant irisin regulates the thermogenic program in fat through ERK and p38 pathways. Recombinant irisin produced in yeast is glycosylated and active. It induces the thermogenic gene program in 3T3-L1 cells and primary subcutaneous adipocytes. In vivo treatments of this recombinant protein in mice show strong anti-obesity effects and improve systematic glucose homeostasis.
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References

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