Scale-up of malaria rapid diagnostic tests and artemisinin-based combination therapy: challenges and perspectives in sub-Saharan Africa

doi:10.1371/journal.pmed.1001590

. 2014 Jan;11(1):e1001590.

doi: 10.1371/journal.pmed.1001590. Epub 2014 Jan 21.

Scale-up of malaria rapid diagnostic tests and artemisinin-based combination therapy: challenges and perspectives in sub-Saharan Africa

Guido J H Bastiaens¹, Teun Bousema², Toby Leslie³

Affiliations

¹ Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
² Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands ; Department of Immunology and Infection, London School of Hygiene & Tropical Medicine, London, United Kingdom.
³ Department of Disease Control, London School of Hygiene & Tropical Medicine, London, United Kingdom.

PMID: 24465186
PMCID: PMC3897367
DOI: 10.1371/journal.pmed.1001590

Scale-up of malaria rapid diagnostic tests and artemisinin-based combination therapy: challenges and perspectives in sub-Saharan Africa

Guido J H Bastiaens et al. PLoS Med. 2014 Jan.

. 2014 Jan;11(1):e1001590.

doi: 10.1371/journal.pmed.1001590. Epub 2014 Jan 21.

Authors

Guido J H Bastiaens¹, Teun Bousema², Toby Leslie³

Affiliations

¹ Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
² Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands ; Department of Immunology and Infection, London School of Hygiene & Tropical Medicine, London, United Kingdom.
³ Department of Disease Control, London School of Hygiene & Tropical Medicine, London, United Kingdom.

PMID: 24465186
PMCID: PMC3897367
DOI: 10.1371/journal.pmed.1001590

Abstract

Guido Bastiaens and colleagues describe barriers to achieving scale-up and appropriate use of rapid diagnostic tests and artemisinin-based combination therapy for malaria in sub-Saharan Africa.

Please see later in the article for the Editors' Summary

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Conflict of interest statement

The authors have declared that no competing interests exist.

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References

1. World Health Organization (2013) World Malaria Report 2013. Geneva: WHO.
1. World Health Organization (2012) T3. Test. Treat. Track. brochure. Geneva: WHO
1. Lubell Y, Reyburn H, Mbakilwa H, Mwangi R, Chonya S, et al. (2008) The impact of response to the results of diagnostic tests for malaria: cost-benefit analysis. BMJ 336: 202–205. - PMC - PubMed
1. Naidoo I, Roper C (2010) Following the path of most resistance: dhps K540E dispersal in African Plasmodium falciparum. Trends Parasitol 26: 447–456. - PubMed
1. Dondorp AM, Yeung S, White L, Nguon C, Day NP, et al. (2010) Artemisinin resistance: current status and scenarios for containment. Nat Rev Microbiol 8: 272–280. - PubMed

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[1] World Health Organization (2013) World Malaria Report 2013. Geneva: WHO.

[2] World Health Organization (2013) World Malaria Report 2013. Geneva: WHO.

[3] World Health Organization (2012) T3. Test. Treat. Track. brochure. Geneva: WHO

[4] World Health Organization (2012) T3. Test. Treat. Track. brochure. Geneva: WHO

[5] Lubell Y, Reyburn H, Mbakilwa H, Mwangi R, Chonya S, et al. (2008) The impact of response to the results of diagnostic tests for malaria: cost-benefit analysis. BMJ 336: 202–205. - PMC - PubMed

[6] Lubell Y, Reyburn H, Mbakilwa H, Mwangi R, Chonya S, et al. (2008) The impact of response to the results of diagnostic tests for malaria: cost-benefit analysis. BMJ 336: 202–205. - PMC - PubMed

[7] Naidoo I, Roper C (2010) Following the path of most resistance: dhps K540E dispersal in African Plasmodium falciparum. Trends Parasitol 26: 447–456. - PubMed

[8] Naidoo I, Roper C (2010) Following the path of most resistance: dhps K540E dispersal in African Plasmodium falciparum. Trends Parasitol 26: 447–456. - PubMed

[9] Dondorp AM, Yeung S, White L, Nguon C, Day NP, et al. (2010) Artemisinin resistance: current status and scenarios for containment. Nat Rev Microbiol 8: 272–280. - PubMed

[10] Dondorp AM, Yeung S, White L, Nguon C, Day NP, et al. (2010) Artemisinin resistance: current status and scenarios for containment. Nat Rev Microbiol 8: 272–280. - PubMed

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Scale-up of malaria rapid diagnostic tests and artemisinin-based combination therapy: challenges and perspectives in sub-Saharan Africa

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Scale-up of malaria rapid diagnostic tests and artemisinin-based combination therapy: challenges and perspectives in sub-Saharan Africa

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