Does Bile Reflux Influence the Progression of Barrett's Esophagus to Adenocarcinoma? (Gastroenterology 2013;145:1300-1311)

Affiliations

Tatsuhiro Masaoka et al. J Neurogastroenterol Motil. 2014 Jan.

. 2014 Jan;20(1):124-6.

doi: 10.5056/jnm.2014.20.1.124. Epub 2013 Dec 30.

¹ Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

No abstract available

Conflict of interest statement

Conflicts of interest: None.

Bile acids increase levels of microRNAs 221 and 222, leading to degradation of CDX2 during esophageal carcinogenesis.
Matsuzaki J, Suzuki H, Tsugawa H, Watanabe M, Hossain S, Arai E, Saito Y, Sekine S, Akaike T, Kanai Y, Mukaisho K, Auwerx J, Hibi T. Matsuzaki J, et al. Gastroenterology. 2013 Dec;145(6):1300-11. doi: 10.1053/j.gastro.2013.08.008. Epub 2013 Aug 8. Gastroenterology. 2013. PMID: 23933602

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