Shrinking indications for azathioprine in Crohn's disease: a conclusion too premature?

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Comment

Haimavati Rammohan et al. Gastroenterology. 2014 Mar.

. 2014 Mar;146(3):866-7.

doi: 10.1053/j.gastro.2013.10.071. Epub 2014 Jan 24.

¹ Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal, Karnataka, India.

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Comment on

Early administration of azathioprine vs conventional management of Crohn's Disease: a randomized controlled trial.
Cosnes J, Bourrier A, Laharie D, Nahon S, Bouhnik Y, Carbonnel F, Allez M, Dupas JL, Reimund JM, Savoye G, Jouet P, Moreau J, Mary JY, Colombel JF; Groupe d'Etude Thérapeutique des Affections Inflammatoires du Tube Digestif (GETAID). Cosnes J, et al. Gastroenterology. 2013 Oct;145(4):758-65.e2; quiz e14-5. doi: 10.1053/j.gastro.2013.04.048. Epub 2013 Apr 30. Gastroenterology. 2013. PMID: 23644079 Clinical Trial.
Early azathioprine therapy is no more effective than placebo for newly diagnosed Crohn's disease.
Panés J, López-Sanromán A, Bermejo F, García-Sánchez V, Esteve M, Torres Y, Domènech E, Piqueras M, Gomez-García M, Gutiérrez A, Taxonera C, Sans M; AZTEC Study Group. Panés J, et al. Gastroenterology. 2013 Oct;145(4):766-74.e1. doi: 10.1053/j.gastro.2013.06.009. Epub 2013 Jun 13. Gastroenterology. 2013. PMID: 23770132 Clinical Trial.