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Randomized Controlled Trial
. 2014 Mar 15;120(6):909-17.
doi: 10.1002/cncr.28355. Epub 2014 Jan 27.

Randomized clinical trial of therapeutic music video intervention for resilience outcomes in adolescents/young adults undergoing hematopoietic stem cell transplant: a report from the Children's Oncology Group

Sheri L Robb  1 , Debra S Burns, Kristin A Stegenga, Paul R Haut, Patrick O Monahan, Jane Meza, Timothy E Stump, Brooke O Cherven, Sharron L Docherty, Verna L Hendricks-Ferguson, Eileen K Kintner, Ann E Haight, Donna A Wall, Joan E Haase
Affiliations
Randomized Controlled Trial

Randomized clinical trial of therapeutic music video intervention for resilience outcomes in adolescents/young adults undergoing hematopoietic stem cell transplant: a report from the Children's Oncology Group

Sheri L Robb et al. Cancer. .

Abstract

Background: To reduce the risk of adjustment problems associated with hematopoietic stem cell transplant (HSCT) for adolescents/young adults (AYAs), we examined efficacy of a therapeutic music video (TMV) intervention delivered during the acute phase of HSCT to: 1) increase protective factors of spiritual perspective, social integration, family environment, courageous coping, and hope-derived meaning; 2) decrease risk factors of illness-related distress and defensive coping; and 3) increase outcomes of self-transcendence and resilience.

Methods: This was a multisite randomized, controlled trial (COG-ANUR0631) conducted at 8 Children's Oncology Group sites involving 113 AYAs aged 11-24 years undergoing myeloablative HSCT. Participants, randomized to the TMV or low-dose control (audiobooks) group, completed 6 sessions over 3 weeks with a board-certified music therapist. Variables were based on Haase's Resilience in Illness Model (RIM). Participants completed measures related to latent variables of illness-related distress, social integration, spiritual perspective, family environment, coping, hope-derived meaning, and resilience at baseline (T1), postintervention (T2), and 100 days posttransplant (T3).

Results: At T2, the TMV group reported significantly better courageous coping (Effect Size [ES], 0.505; P = .030). At T3, the TMV group reported significantly better social integration (ES, 0.543; P = .028) and family environment (ES, 0.663; P = .008), as well as moderate nonsignificant effect sizes for spiritual perspective (ES, 0.450; P = .071) and self-transcendence (ES, 0.424; P = .088).

Conclusions: The TMV intervention improves positive health outcomes of courageous coping, social integration, and family environment during a high-risk cancer treatment. We recommend the TMV be examined in a broader population of AYAs with high-risk cancers.

Keywords: adolescents; cancer; courageous coping; family relations; music; music therapy; resilience; self-transcendence; social environment; young adult.

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Figures

Figure 1
Figure 1
Exploratory RIM guiding the study. Reprint permission: Haase JE, Kintner EK, Monahan PO, Robb SL. The resilience in illness model, Part 1: exploratory evaluation in adolescents and young adults with cancer. Cancer Nurs. 2013:March 20.
Figure 2
Figure 2
CONSORT diagram for trial accrual, intervention delivery, and data collection. Note: The death rate did not differ significantly between the two arms (two-sided Fisher exact test, p = .21).
See this image and copyright information in PMC

References

    1. Barrera M, Atenafu E, Pinto J, Barrera M, Atenafu E, Pinto J. Behavioral, social, and educational outcomes after pediatric stem cell transplantation and related factors. Cancer. 2009;115:880–889. - PubMed
    1. Kupst MJ, Penati B, Debban B, et al. Cognitive and psychosocial functioning of pediatric hematopoietic stem cell transplant patients: a prospective longitudinal study. Bone Marrow Transplant. 2002;30:609–617. - PubMed
    1. Millar B, Patterson P, Desille N. Emerging adulthood and cancer: how unmet needs vary with time-since-treatment. Palliat Support Care. 2010;8:151–158. - PubMed
    1. Syrjala KL, Stover AC, Yi JC, Artherholt SB, Abrams JR. Measuring social activities and social function in long-term cancer survivors who received hematopoietic stem cell transplantation. Psychooncology. 2010;19:462–471. - PMC - PubMed
    1. Haase JE, Peterson S. Resilience. In: Peterson S, Bredow TS, editors. Middle Range Theories: Application to Nursing Research. 3rd ed. 2013. pp. 256–284.

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