Review
doi: 10.1007/BF00762301.
Gramicidin A--phospholipid model systems
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- PMID: 2447070
- DOI: 10.1007/BF00762301
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Review
Gramicidin A--phospholipid model systems
J Bioenerg Biomembr.
1987 Dec.
Abstract
Gramicidin A forms ion-conducting channels which can traverse the hydrocarbon core of lipid bilayer membranes. The structures formed by gramicidin A are among the best characterized of all membrane-bound polypeptides or proteins. In this review a brief summary is given of the occurrence, conformation, and synthesis of gramicidin A, and of its use as a model for ion transport and the interaction of proteins and lipids in biological membranes.
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