Gramicidin A--phospholipid model systems
- PMID: 2447070
- DOI: 10.1007/BF00762301
Gramicidin A--phospholipid model systems
Abstract
Gramicidin A forms ion-conducting channels which can traverse the hydrocarbon core of lipid bilayer membranes. The structures formed by gramicidin A are among the best characterized of all membrane-bound polypeptides or proteins. In this review a brief summary is given of the occurrence, conformation, and synthesis of gramicidin A, and of its use as a model for ion transport and the interaction of proteins and lipids in biological membranes.