Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Mar 7;4(1):e20.
doi: 10.4081/idr.2012.e20. eCollection 2012 Jan 2.

Screening and detection of heterogenous vancomycin intermediate Staphylococcus aureus in Hospital Kuala Lumpur Malaysia, using the glycopeptide resistance detection Etest and population analysis profiling

Siti Roszilawati Ramli  1 , Hui-Min Neoh  2 , Muhammad Nazri Aziz  3 , Salasawati Hussin  4
Affiliations

Screening and detection of heterogenous vancomycin intermediate Staphylococcus aureus in Hospital Kuala Lumpur Malaysia, using the glycopeptide resistance detection Etest and population analysis profiling

Siti Roszilawati Ramli et al. Infect Dis Rep. .

Abstract

In a 3-month study done in Hospital Kuala Lumpur (HKL), 7 out of 320 methicillin resistant Staphylococcus aureus isolates were confirmed as heterogeneous vancomycin intermediate S. aureus (hVISA) using the glycopeptide resistance detection e-test and population analysis, giving a prevalence rate of 2.19%. This is the first report of hVISA in Malaysia.

Keywords: Hospital Kuala Lumpur.; heterogenous vancomycin intermediate Staphylococcus aureus (hVISA).

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: all other authors report no conflicts of interest.

References

    1. Hiramatsu K, Aritaka N, Hanaki H, et al. Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin. Lancet. 1997;350:1670–3. - PubMed
    1. Howden BP, Davies JK, Johnson PDR, et al. Reduced vancomycin susceptibility in Staphylococcus aureus, including vancomycin intermediate and heterogenous vancomycin-intermediate strains: resistant mechanism, laboratory detection and clinical implications. Clin Microbiol Rev. 2010;23:99–139. - PMC - PubMed
    1. Hanaki H, Kuwahara-Arai K, Boyel-Vavra S, et al. Activated cell-wall synthesis is associated with vancomycin resistance in methicillin-resistant Staphylococcus aureus clinical strains Mu3 and Mu50. J Antimicrob Chemother. 1998;42:199–209. - PubMed
    1. Song JH, Hiramatsu K, Suh JY, et al. Emergence in Asian countries of Staphylococcus aureus with reduced susceptibility to vancomycin. Antimicrob Agents Chemother. 2004;48:4926–8. - PMC - PubMed
    1. National surveillance of antibiotic resistance 2008. Available from: www.imr.gov.my/report/nsar.htm.

LinkOut - more resources