Successful treatment of Leuconostoc bacteremia in a neutropenic patient with tigecycline

doi:10.4081/idr.2012.e31

Case Reports

. 2012 Apr 27;4(2):e31.

doi: 10.4081/idr.2012.e31.

Successful treatment of Leuconostoc bacteremia in a neutropenic patient with tigecycline

Trupti Patel¹, Aoife Molloy², Robin Smith¹, Indran Balakrishnan¹

Affiliations

¹ Department of Microbiology, Royal Free Hospital NHS Foundation Trust, London;
² Department of Infectious Diseases, Ealing Hospital, Ealing Hospital NHS Trust, Southall, UK.

PMID: 24470945
PMCID: PMC3892628
DOI: 10.4081/idr.2012.e31

Case Reports

Successful treatment of Leuconostoc bacteremia in a neutropenic patient with tigecycline

Trupti Patel et al. Infect Dis Rep. 2012.

. 2012 Apr 27;4(2):e31.

doi: 10.4081/idr.2012.e31.

Authors

Trupti Patel¹, Aoife Molloy², Robin Smith¹, Indran Balakrishnan¹

Affiliations

¹ Department of Microbiology, Royal Free Hospital NHS Foundation Trust, London;
² Department of Infectious Diseases, Ealing Hospital, Ealing Hospital NHS Trust, Southall, UK.

PMID: 24470945
PMCID: PMC3892628
DOI: 10.4081/idr.2012.e31

Abstract

Leuconostoc lactis is a recognised cause of infection in immunocompromised hosts. It is intrinsically resistant to multiple antibiotics and treatment options may be limited. We report a case of safe and effective use of tigecycline in the treatment of Leuconostoc catheter-related line sepsis in a neutropenic patient. To our knowledge, this is the first reported case of successful use of tigecycline for Leuconostoc bacteremia.

Keywords: Leuconostoc; bacteremia; immunocompromise; neutropenia.; tigecycline.

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Conflict of interest statement

Conflict of interests: the authors report no conflict of interests.

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References

1. Freifeld AG, Bow EJ, Sepkowitz KA, et al. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america. Clin Infect Dis. 2011;52:e56–93. - PubMed
1. Bernstein WB, Trotta RF, Rector JT, et al. Mechanisms for linezolid-induced anemia and thrombocytopenia. Ann Pharmacother. 2003;37:517–20. - PubMed
1. Arias CA, Murray BE. Enterococcus species, Streptococcus bovis group and Leuconostoc species. In: Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas, and Bennett's principles and practice of infectious diseases. 7th edn. Philadelphia: Churchill Livingstone/Elsevier; 2009.
1. Albanese A, Spanu T, Sali M, et al. Molecular identification of Leuconostoc mesenteroides as a cause of brain abscess in an immunocompromised patient. J Clin Microbiol. 2006;44:3044–5. - PMC - PubMed
1. Buu-Hoi A, Branger C, Acar JF. Vancomycin-resistant streptococci or Leuconostoc sp. Antimicrob Agents Chemother. 1985;28:458–60. - PMC - PubMed

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[1] Freifeld AG, Bow EJ, Sepkowitz KA, et al. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america. Clin Infect Dis. 2011;52:e56–93. - PubMed

[2] Freifeld AG, Bow EJ, Sepkowitz KA, et al. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america. Clin Infect Dis. 2011;52:e56–93. - PubMed

[3] Bernstein WB, Trotta RF, Rector JT, et al. Mechanisms for linezolid-induced anemia and thrombocytopenia. Ann Pharmacother. 2003;37:517–20. - PubMed

[4] Bernstein WB, Trotta RF, Rector JT, et al. Mechanisms for linezolid-induced anemia and thrombocytopenia. Ann Pharmacother. 2003;37:517–20. - PubMed

[5] Arias CA, Murray BE. Enterococcus species, Streptococcus bovis group and Leuconostoc species. In: Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas, and Bennett's principles and practice of infectious diseases. 7th edn. Philadelphia: Churchill Livingstone/Elsevier; 2009.

[6] Arias CA, Murray BE. Enterococcus species, Streptococcus bovis group and Leuconostoc species. In: Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas, and Bennett's principles and practice of infectious diseases. 7th edn. Philadelphia: Churchill Livingstone/Elsevier; 2009.

[7] Albanese A, Spanu T, Sali M, et al. Molecular identification of Leuconostoc mesenteroides as a cause of brain abscess in an immunocompromised patient. J Clin Microbiol. 2006;44:3044–5. - PMC - PubMed

[8] Albanese A, Spanu T, Sali M, et al. Molecular identification of Leuconostoc mesenteroides as a cause of brain abscess in an immunocompromised patient. J Clin Microbiol. 2006;44:3044–5. - PMC - PubMed

[9] Buu-Hoi A, Branger C, Acar JF. Vancomycin-resistant streptococci or Leuconostoc sp. Antimicrob Agents Chemother. 1985;28:458–60. - PMC - PubMed

[10] Buu-Hoi A, Branger C, Acar JF. Vancomycin-resistant streptococci or Leuconostoc sp. Antimicrob Agents Chemother. 1985;28:458–60. - PMC - PubMed

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Successful treatment of Leuconostoc bacteremia in a neutropenic patient with tigecycline

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Successful treatment of Leuconostoc bacteremia in a neutropenic patient with tigecycline

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