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. 2014 Jun 15;209(12):1870-2.
doi: 10.1093/infdis/jiu068. Epub 2014 Jan 28.

Stillbirth during infection with Middle East respiratory syndrome coronavirus

Daniel C Payne  1 , Ibrahim Iblan  2 , Sultan Alqasrawi  3 , Mohannad Al Nsour  4 , Brian Rha  5 , Rania A Tohme  6 , Glen R Abedi  1 , Noha H Farag  7 , Aktham Haddadin  8 , Tarek Al Sanhouri  8 , Najwa Jarour  3 , David L Swerdlow  1 , Denise J Jamieson  9 , Mark A Pallansch  1 , Lia M Haynes  1 , Susan I Gerber  1 , Mohammad Mousa Al Abdallat  3 ; Jordan MERS-CoV Investigation Team
Collaborators, Affiliations

Stillbirth during infection with Middle East respiratory syndrome coronavirus

Daniel C Payne et al. J Infect Dis. .

Abstract

We conducted an epidemiologic investigation among survivors of an outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Jordan. A second-trimester stillbirth occurred during the course of an acute respiratory illness that was attributed to MERS-CoV on the basis of exposure history and positive results of MERS-CoV serologic testing. This is the first occurrence of stillbirth during an infection with MERS-CoV and may have bearing upon the surveillance and management of pregnant women in settings of unexplained respiratory illness potentially due to MERS-CoV. Future prospective investigations of MERS-CoV should ascertain pregnancy status and obtain further pregnancy-related data, including biological specimens for confirmatory testing.

Keywords: EMC-CoV; Jordan; MERS-CoV; Middle East respiratory syndrome; birth outcomes; novel coronavirus; pneumonia; pregnancy; severe acute respiratory illness; stillbirth.

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Figures

Figure 1.
Figure 1.
Timeline of events associated with a stillbirth attributable to Middle East respiratory syndrome coronavirus (MERS-CoV) infection, 1–30 April 2012.
See this image and copyright information in PMC

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