doi: 10.1128/mcb.8.1.502-504.1988.
Developmental expression of two forms of pp60c-src in mouse brain
Affiliations
- PMID: 2447488
- PMCID: PMC363161
- DOI: 10.1128/mcb.8.1.502-504.1988
Item in Clipboard
Developmental expression of two forms of pp60c-src in mouse brain
Mol Cell Biol.
1988 Jan.
Abstract
The expression during mouse development of two forms of protein-tyrosine kinase pp60c-src, pp60 and pp60+, was investigated. At embryonic day 9 (E9), only pp60 was detected in whole-brain lysates. A trace of pp60+ was first seen at E10. In E18 embryos and in adults, pp60+ was the predominant form of pp60c-src in forebrain and midbrain lysates.
Similar articles
-
An altered form of pp60c-src is expressed primarily in the central nervous system.Mol Cell Biol. 1987 Nov;7(11):4115-7. doi: 10.1128/mcb.7.11.4115-4117.1987. Mol Cell Biol. 1987. PMID: 2448603 Free PMC article.
-
pp60c-src is expressed in human fetal and adult brain.Am J Pathol. 1985 Apr;119(1):151-7. Am J Pathol. 1985. PMID: 2580441 Free PMC article.
-
A protein tyrosine kinase involved in regulation of pp60c-src function.J Biol Chem. 1989 Dec 15;264(35):20886-93. J Biol Chem. 1989. PMID: 2480346
-
Tyrosine phosphorylation of membrane-associated tubulin in nerve growth cones enriched in pp60c-src.Ciba Found Symp. 1990;150:57-69; discussion 69-78. doi: 10.1002/9780470513927.ch5. Ciba Found Symp. 1990. PMID: 2115426 Review.
-
Localization of the normal cellular src protein to the growth cone of differentiating neurons in brain and retina.Adv Exp Med Biol. 1990;265:117-25. doi: 10.1007/978-1-4757-5876-4_10. Adv Exp Med Biol. 1990. PMID: 1696060 Review.
Cited by
-
SRC Kinase Isoforms Regulate mRNA Splicing during Neural Development.J Neurosci. 2025 Aug 20;45(34):e1705242025. doi: 10.1523/JNEUROSCI.1705-24.2025. J Neurosci. 2025. PMID: 40750357 Free PMC article.
-
The hypophyseal pars tuberalis is enriched with distinct phosphotyrosine-containing proteins not detected in other areas of the brain and pituitary.Cell Tissue Res. 1993 Jun;272(3):499-507. doi: 10.1007/BF00318556. Cell Tissue Res. 1993. PMID: 7687928
-
Early activation of endogenous pp60src kinase activity during neuronal differentiation of cultured human neuroblastoma cells.Mol Cell Biol. 1990 Jan;10(1):361-70. doi: 10.1128/mcb.10.1.361-370.1990. Mol Cell Biol. 1990. PMID: 2136766 Free PMC article.
-
Expression of developmentally relevant proteins by rodent embryo CNS cells in vivo and in vitro: proto-oncogene pp60c-src and high molecular weight neurofilament protein.Cell Biol Toxicol. 1992 Apr-Jun;8(2):113-28. doi: 10.1007/BF00260562. Cell Biol Toxicol. 1992. PMID: 1384943
-
The sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-src.Mol Cell Biol. 1993 Apr;13(4):2391-400. doi: 10.1128/mcb.13.4.2391-2400.1993. Mol Cell Biol. 1993. PMID: 7681147 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous
