Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2012 Apr;1(1):17-22.
doi: 10.5812/jnp.5. Epub 2012 Apr 5.

Turmeric: Reemerging of a neglected Asian traditional remedy

Parviz Khajehdehi  1
Affiliations
Review

Turmeric: Reemerging of a neglected Asian traditional remedy

Parviz Khajehdehi. J Nephropathol. 2012 Apr.

Abstract

Context: Turmeric (Curcuma longa) is a wild plant of the ginger family native to tropical South Asia.

Evidence acquisitions: Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched.

Results: Emerging evidence indicate that turmeric/curcumin inhibits cytokines and TGF-β production. From the various factors involved in the genesis of chronic kidney disease and pathogenesis of primary and secondary glomerulonehritis, TGF-β has emerged as a key factor in the cascade of events. Leading to glomerulosclerosis, tubulointerstitial fibrosis and end-stage renal disease.

Conclusions: considering the inhibitory effect of turmeric/curcumin on cytokines and TGF-β, it seems wise to assume that supplementary turmeric/curcumin might be a candidate remedy for chronic kidney disease and possibly prevention of subsequent end stage renal disease.

Keywords: Chronic kidney disease; Curcumin; End stage renal disease; Turmeric.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Chan E, Lim Y, Wong S, Lim K, Tan S, Lianto F. et al. Effects of different drying methods on the antioxidant properties of leaves and tea of ginger species. Food chemistry . 2009;113(1):166–72.
    1. Lin JK, Chen YC, Huang YT, Lin-Shiau SY. Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin. Journal of Cellular Biochemistry . 1997;67(S28-29):39–48. - PubMed
    1. Lin LI, Ke YF, Ko YC, Lin JK. Curcumin inhibits SK-Hep-1 hepatocellular carcinoma cell invasion in vitro and suppresses matrix metalloproteinase-9 secretion. Oncology . 1998;55(4):349–53. - PubMed
    1. Henrotin Y, Clutterbuck AL, Allaway D, Lodwig EM, Harris P, Mathy-Hartert M. et al. Biological actions of curcumin on articular chondrocytes. Osteoarthritis Cartilage . 2010;18(2):141–9. - PubMed
    1. Gregory PJ, Sperry M, Wilson AF. Dietary supplements for osteoarthritis. Am Fam Physician . 2008;77(2):177–84. - PubMed

LinkOut - more resources