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Case Reports
. 2014 Jan 30;370(5):486-8.
doi: 10.1056/NEJMc1304828.

Maraviroc and JC virus-associated immune reconstitution inflammatory syndrome

Paul S Giacomini  1 , Ayal Rozenberg, Imke Metz, David Araujo, Nathalie Arbour, Amit Bar-Or; Maraviroc in Multiple Sclerosis–Associated PML–IRIS (MIMSAPI) Group
Collaborators, Affiliations
Case Reports

Maraviroc and JC virus-associated immune reconstitution inflammatory syndrome

Paul S Giacomini et al. N Engl J Med. .
No abstract available

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Figures

Figure 1
Figure 1. Sequential Magnetic Resonance Images of the Brain
When the patient presented for treatment, axial fluid-attenuated inversion recovery images showed multilobar progressive multifocal leukoencephalopathy (Panels A and B). A T1-weighted image after gadolinium infusion showed frank immune reconstitution inflammatory syndrome (IRIS) after the patient discontinued maraviroc (Panel C). After the patient began to receive maraviroc again, a T1-weighted image after gadolinium infusion showed regression of IRIS (Panel D). A T1-weighted image after gadolinium infusion obtained 2 months after gradual discontinuation of maraviroc showed stable lesions with no enhancement (Panel E).
See this image and copyright information in PMC

References

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