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Comment
. 2014 Jan 30;505(7485):621-2.
doi: 10.1038/505621a.

Molecular biology: A second layer of information in RNA

Silvia B V Ramos  1 , Alain Laederach  1
Affiliations
Comment

Molecular biology: A second layer of information in RNA

Silvia B V Ramos et al. Nature. .

Abstract

Three studies have characterized the full complement of RNA folding in cells. They find large numbers of secondary structures in RNA, some of which may have functional consequences for the cell.

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Figures

Figure 1
Figure 1. Principles of RNA primary sequence and secondary structure
a, RNA is a single-stranded polymer, with bases adenine (A), cytosine (C), guanine (G) and uracil (U). b, Unlike DNA, RNA molecules do not pair up to form helices. The bases of an individual molecule can therefore pair with one another (G–C and A–U), causing the RNA to fold into secondary structures. Three reports,, find that such folding is commonplace in humans, plants and yeast.
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