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. 2014 Feb;52(2):627-31.
doi: 10.1128/JCM.02422-13. Epub 2013 Nov 13.

Nosocomial outbreak of Salmonella enterica serovar Typhimurium primarily affecting a pediatric ward in South Africa in 2012

Anthony M Smith  1 , Mnikelwa A Mthanti, Carel Haumann, Nomalungisa Tyalisi, Gerald P G Boon, Arvinda Sooka, Karen H Keddy; GERMS-SA Surveillance Network
Affiliations

Nosocomial outbreak of Salmonella enterica serovar Typhimurium primarily affecting a pediatric ward in South Africa in 2012

Anthony M Smith et al. J Clin Microbiol. 2014 Feb.

Abstract

We describe a nosocomial outbreak of diarrheal disease caused by extended-spectrum β-lactamase-producing multidrug-resistant Salmonella enterica serovar Typhimurium, focused on a pediatric ward in South Africa. The outbreak peaked between May 2012 and July 2012. Person-to-person transmission was the most likely mechanism of spread of the infection, expedited due to a breakdown in hand-washing and hygiene, suboptimal infection control practices, overcrowding of hospital wards, and an undesirable nurse-to-patient ratio.

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Figures

FIG 1
FIG 1
Number of human isolates of Salmonella Typhimurium with an antimicrobial susceptibility profile (including ESBL production) identical to that of the current outbreak strain, for isolates from the same district as the outbreak strain, March 2011 to March 2013. Importantly, these data show only the number of isolates received and investigated by the CED.
FIG 2
FIG 2
PFGE patterns (XbaI digestion) associated with Salmonella Typhimurium strains isolated in the province in which the nosocomial outbreak occurred. The outbreak pattern is indicated for comparison to other/background patterns identified in the province.
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