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Comparative Study
. 2014 Feb;52(2):671-3.
doi: 10.1128/JCM.03113-13. Epub 2013 Dec 11.

A cost-effective approach for detection of toxigenic Clostridium difficile: toxigenic culture using ChromID Clostridium difficile agar

Shik Luk  1 , Wing Kin To, Tak Keung Ng, Wai Ting Hui, Wing Keung Lee, Florence Lau, Almond Man Wai Ching
Affiliations
Comparative Study

A cost-effective approach for detection of toxigenic Clostridium difficile: toxigenic culture using ChromID Clostridium difficile agar

Shik Luk et al. J Clin Microbiol. 2014 Feb.

Abstract

We evaluated the performance and the cost of toxigenic culture using a commercial chromogenic medium (CDIF) for 538 stool specimens. Compared with real-time PCR, this method was found to detect an additional 9% of positive specimens and result in 61% reduction in material costs, with a trade-off increase in turnaround time of 1 day.

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FIG 1
FIG 1
Results of the diagnostic algorithm using toxigenic culture.
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