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. 2014 Jan 24:8:3.
doi: 10.3389/fncom.2014.00003. eCollection 2014.

Data and model tango to aid the understanding of astrocyte-neuron signaling

Shivendra Tewari  1 , Vladimir Parpura  2
Affiliations

Data and model tango to aid the understanding of astrocyte-neuron signaling

Shivendra Tewari et al. Front Comput Neurosci. .
No abstract available

Keywords: astrocytes; mathematical model; neurons; signaling; tripartite synapse.

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Figures

Figure 1
Figure 1
The “tango” between experimental data and mathematical model is necessary for a faster and deeper understanding of the role of astrocyte-neuron signaling in the brain. Experimental data are important for signaling pathway quantification using mathematical models. The experimental data in turn can gain from the model by testing a hypothesis in silico or designing new experiments to test the hypothesis in vivo or in vitro. It is a combination of both the approaches that could lead us to a wholesome understanding of the human brain, i.e., the holy grail of neuroscience.
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