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. 2014 Mar;20(3):294-5.
doi: 10.1111/cns.12230. Epub 2014 Jan 31.

NLRP3 inflammasome: a new target in major depressive disorder

Elísabet Alcocer-Gómez  1 , Mario D Cordero
Affiliations

NLRP3 inflammasome: a new target in major depressive disorder

Elísabet Alcocer-Gómez et al. CNS Neurosci Ther. 2014 Mar.
No abstract available

Keywords: Antidepressants; Depression; Inflammasome.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Menu P, Vince JE. The NLRP3 inflammasome in health and disease: the good, the bad and the ugly. Clin Exp Immunol 2011;166:1–15. - PMC - PubMed
    1. Leemans JC, Cassel SL, Sutterwala FS. Sensing damage by the NLRP3 inflammasome. Immunol Rev 2011;243:152–162. - PMC - PubMed
    1. Iwata M, Ota KT, Duman RS. The inflammasome: pathways linking psychological stress, depression, and systemic illnesses. Brain Behav Immun 2013;31:105–114. - PMC - PubMed
    1. Zhang Y, Liu L, Peng YL, et al. Involvement of inflammasome activation in lipopolysaccharide‐induced mice depressive‐like behaviors. CNS Neurosci Ther 2013; 20:119–124. - PMC - PubMed
    1. Alcocer‐Gómez E, de Miguel M, Casas‐Barquero N, et al. NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder. Brain Behav Immun 2013;36:111–117. - PubMed

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