[Mechanism of postextrasystolic potentiation of the myocardium]
[Article in
Russian]
- PMID: 2448171
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[Mechanism of postextrasystolic potentiation of the myocardium]
[Article in
Russian]
Fiziol Zh SSSR Im I M Sechenova.
1987 Oct.
Abstract
Combined effects of poststimulation and postextrasystolic potentiation (PESP) were studied in the rat papillary muscles. The constant PESP augmentation of isometric force triggered by extrasystolic stimulus was shown for 2-8 poststimulatory potentiated contractions. The PESP was not dependent upon the Ca2+ concentration within the 0.5-1.2 mM range. The findings corroborate the postulate that the PESP in cardiomyocytes is associated with special Ca2+ store which is triggered by two APs: regular and extrasystolic ones.
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