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. 1988 Jan 14;331(6152):143-5.
doi: 10.1038/331143a0.

Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes

L C Timpe  1 , T L Schwarz, B L Tempel, D M Papazian, Y N Jan, L Y Jan
Affiliations

Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes

L C Timpe et al. Nature. .

Abstract

The Shaker gene of Drosophila melanogaster encodes a potassium-selective ion channel, the 'A' channel, or one of its subunits. A single Shaker messenger RNA species suffices to direct the synthesis of functional A channels in Xenopus oocytes. Physiological characteristics of the A currents induced by two different mRNA species are compared.

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