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. 1991;4(3):129-41.
doi: 10.3233/BEN-1991-4301.

Cognitive function in multiple sclerosis: a subcortical pattern of neuropsychological impairment?

C Caltagirone  1 , G A Carlesimo  1 , L Fadda  1 , S Roncacci  1
Affiliations

Cognitive function in multiple sclerosis: a subcortical pattern of neuropsychological impairment?

C Caltagirone et al. Behav Neurol. 1991.

Abstract

In order to evaluate cognitive impairment in multiple sclerosis (MS) neuropsychological tests were administered to 25 patients with clinically definite disease. Four (16%) showed diffuse cognitive impairment, whereas the others, compared with controls showed a specific deficit on tests known to be sensitive to frontal lobe damage. These results are interpreted in the light of current hypotheses relating to subcortical contributions in cognition.

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