Retention rates of infliximab and tocilizumab during a 3-year period in a Brazilian hospital
- PMID: 24488390
- PMCID: PMC4880388
- DOI: 10.1590/s1679-45082013000400015
Retention rates of infliximab and tocilizumab during a 3-year period in a Brazilian hospital
Abstract
Objective: To compare the efficacy and the period of use of tocilizumab and infliximab during treatment of rheumatoid arthritis patients.
Methods: The period of use of two biologics with different mechanisms of action were compared in treatment of rheumatoid arthritis patients.
Res ults: Both medications showed efficacy, but the period of use with no loss of efficacy was longer in patients receiving tocilizumab when compared to infliximab.
Conclusion: Tocilizumab maintains a period of use significantly longer as compared with infliximab in patients with rheumatoid arthritis treated at a single organization.
Objetivo:: Comparar a eficácia e período de uso de tocilizumabe e infliximabe no tratamento de pacientes com artrite reumatoide.
Métodos:: Foi comparado o tempo de uso de dois biológicos com diferentes mecanismos de ação no tratamento de pacientes com artrite reumatoide.
Resultados:: Ambos os biológicos se mostraram eficazes, mas o tempo de uso sem perda de eficácia foi maior com tocilizumabe quando comparado ao infliximabe.
Conclusão:: Tocilizumabe mantém um período de uso significativamente maior do que infliximabe em pacientes com artrite reumatoide tratados em uma única instituição.
Conflict of interest statement
Conflict of interest: none.
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