Retinopathy of prematurity. Pathologic correlation of clinical stages

Abstract

This article details the pathologic features of recently described clinical stages of vitreoretinopathy associated with premature birth in humans, beginning with a review of retinal angiogenesis in humans and then of the five stages of retinopathy of prematurity, with a description of paramount clinical feature in each stage and then corresponding pathologic changes. The article concludes with a consideration of arrested and reactivated retinopathy.