NIMH Project Accept (HPTN 043): results from in-depth interviews with a longitudinal cohort of community members
- PMID: 24489841
- PMCID: PMC3906114
- DOI: 10.1371/journal.pone.0087091
NIMH Project Accept (HPTN 043): results from in-depth interviews with a longitudinal cohort of community members
Abstract
Introduction: NIMH Project Accept (HPTN 043) is a community- randomized trial to test the safety and efficacy of a community-level intervention designed to increase testing and lower HIV incidence in Tanzania, Zimbabwe, South Africa and Thailand. The evaluation design included a longitudinal study with community members to assess attitudinal and behavioral changes in study outcomes including HIV testing norms, HIV-related discussions, and HIV-related stigma.
Methods: A cohort of 657 individuals across all sites was selected to participate in a qualitative study that involved 4 interviews during the study period. Baseline and 30-month data were summarized according to each outcome, and a qualitative assessment of changes was made at the community level over time.
Results: Members from intervention communities described fewer barriers and greater motivation for testing than those from comparison communities. HIV-related discussions in intervention communities were more grounded in personal testing experiences. A change in HIV-related stigma over time was most pronounced in Tanzania and Zimbabwe. Participants in the intervention communities from these two sites attributed community-level changes in attitudes to project specific activities.
Discussion: The Project Accept intervention was associated with more favorable social norms regarding HIV testing, more personal content in HIV discussions in all study sites, and qualitative changes in HIV-related stigma in two of five sites.
Conflict of interest statement
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References
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- Creswell JW, Plan VL (2011) Designing and Conducting Mixed Methods Research, 2nd Edition. Sage Publications. Thousand Oaks, CA.
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- 097410/Wellcome Trust/United Kingdom
- U01 MH066687/MH/NIMH NIH HHS/United States
- U01AI068613/AI/NIAID NIH HHS/United States
- U01AI068617/AI/NIAID NIH HHS/United States
- U01 AI068617/AI/NIAID NIH HHS/United States
- U01MH066687/MH/NIMH NIH HHS/United States
- U01 AI068613/AI/NIAID NIH HHS/United States
- U01MH066702/MH/NIMH NIH HHS/United States
- U01 MH066701/MH/NIMH NIH HHS/United States
- U01MH066701/MH/NIMH NIH HHS/United States
- U01 MH066688/MH/NIMH NIH HHS/United States
- U01MH066688/MH/NIMH NIH HHS/United States
- UM1A068619/PHS HHS/United States
- U01 MH066702/MH/NIMH NIH HHS/United States
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