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. 2014 Jul;28(7):1548-52.
doi: 10.1038/leu.2014.59. Epub 2014 Feb 5.

Serial exome analysis of disease progression in premalignant gammopathies

S Zhao  1 , M Choi  2 , C Heuck  3 , S Mane  4 , B Barlogie  3 , R P Lifton  5 , M V Dhodapkar  6
Affiliations

Serial exome analysis of disease progression in premalignant gammopathies

S Zhao et al. Leukemia. 2014 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest:

The authors disclose no conflict of interest.

Figures

Figure 1
Figure 1
Analysis of somatic variants 1a. Number of somatic variants per sample. 1b. Serial analysis of somatic variants in each patients 1c. Analysis of B allele frequencies in paired samples.
Figure 1
Figure 1
Analysis of somatic variants 1a. Number of somatic variants per sample. 1b. Serial analysis of somatic variants in each patients 1c. Analysis of B allele frequencies in paired samples.
Figure 1
Figure 1
Analysis of somatic variants 1a. Number of somatic variants per sample. 1b. Serial analysis of somatic variants in each patients 1c. Analysis of B allele frequencies in paired samples.
Figure 2
Figure 2
Analysis of genomic gains/losses with disease progression 2a. Analysis of LOH patterns. 2b. Analysis of CNV pattern in chromosome 17 in patient P3 2c. Analysis of CNV pattern in chromosome 8 in patient P2 2d. Analysis of copy number variations 2e. Comparison of mutational profile with published data in patients with clinical myeloma.
Figure 2
Figure 2
Analysis of genomic gains/losses with disease progression 2a. Analysis of LOH patterns. 2b. Analysis of CNV pattern in chromosome 17 in patient P3 2c. Analysis of CNV pattern in chromosome 8 in patient P2 2d. Analysis of copy number variations 2e. Comparison of mutational profile with published data in patients with clinical myeloma.
Figure 2
Figure 2
Analysis of genomic gains/losses with disease progression 2a. Analysis of LOH patterns. 2b. Analysis of CNV pattern in chromosome 17 in patient P3 2c. Analysis of CNV pattern in chromosome 8 in patient P2 2d. Analysis of copy number variations 2e. Comparison of mutational profile with published data in patients with clinical myeloma.
Figure 2
Figure 2
Analysis of genomic gains/losses with disease progression 2a. Analysis of LOH patterns. 2b. Analysis of CNV pattern in chromosome 17 in patient P3 2c. Analysis of CNV pattern in chromosome 8 in patient P2 2d. Analysis of copy number variations 2e. Comparison of mutational profile with published data in patients with clinical myeloma.
Figure 2
Figure 2
Analysis of genomic gains/losses with disease progression 2a. Analysis of LOH patterns. 2b. Analysis of CNV pattern in chromosome 17 in patient P3 2c. Analysis of CNV pattern in chromosome 8 in patient P2 2d. Analysis of copy number variations 2e. Comparison of mutational profile with published data in patients with clinical myeloma.
See this image and copyright information in PMC

References

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