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. 1988 Feb;51(2):277-80.
doi: 10.1136/jnnp.51.2.277.

Multiple sclerosis: correlation of magnetic resonance imaging with cerebrospinal fluid findings

L S Honig  1 , R Siddharthan, W A Sheremata, J J Sheldon, A Sazant
Affiliations

Multiple sclerosis: correlation of magnetic resonance imaging with cerebrospinal fluid findings

L S Honig et al. J Neurol Neurosurg Psychiatry. 1988 Feb.

Abstract

MRI examination of 41 patients with clinical definite multiple sclerosis showed white matter lesions of high proton T2 signal consistent with demyelination in 76% and CSF abnormalities present in 76%. Of patients with CSF abnormalities, 26% had normal MRI scans; conversely 26% of patients with MRI abnormalities had negative CSF studies. Thus a significant number of multiple sclerosis patients had negative results on either MRI or CSF examination, while only 5% had normal results on both tests.

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