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Multicenter Study
. 2014 Feb 7:14:21.
doi: 10.1186/1471-230X-14-21.

Chronic gastritis in China: a national multi-center survey

Yiqi Du, Yu Bai, Pei Xie, Jingyuan Fang, Xiaozhong Wang, Xiaohua Hou, Dean Tian, Chengdang Wang, Yandi Liu, Weihong Sha, Bangmao Wang, Yanqing Li, Guoliang Zhang, Yan Li, Ruihua Shi, Jianming Xu, Youming Li, Minghe Huang, Shengxi Han, Jie Liu, Xu Ren, Pengyan Xie, Zhangliu Wang, Lihong Cui, Jianqiu Sheng, Hesheng Luo, Zhaohui Wang, Xiaoyan Zhao, Ning Dai, Yuqiang Nie, Yiyou Zou, Bing Xia, Zhining Fan, Zhitan Chen, Sanren Lin, Zhao-Shen Li  1 ; Chinese Chronic Gastritis Research group
Affiliations
Multicenter Study

Chronic gastritis in China: a national multi-center survey

Yiqi Du et al. BMC Gastroenterol. .

Abstract

Background: Chronic gastritis is one of the most common findings at upper endoscopy in the general population, and chronic atrophic gastritis is epidemiologically associated with the occurrence of gastric cancer. However, the current status of diagnosis and treatment of chronic gastritis in China is unclear.

Methods: A multi-center national study was performed; all patients who underwent diagnostic upper endoscopy for evaluation of gastrointestinal symptoms from 33 centers were enrolled. Data including sex, age, symptoms and endoscopic findings were prospectively recorded.

Results: Totally 8892 patients were included. At endoscopy, 4389, 3760 and 1573 patients were diagnosed to have superficial gastritis, erosive gastritis, and atrophic gastritis, respectively. After pathologic examination, it is found that atrophic gastritis, intestinal metaplasia and dysplasia were prevalent, which accounted for 25.8%, 23.6% and 7.3% of this patient population. Endoscopic features were useful for predicting pathologic atrophy (PLR = 4.78), but it was not useful for predicting erosive gastritis. Mucosal-protective agents and PPI were most commonly used medications for chronic gastritis.

Conclusions: The present study suggests non-atrophic gastritis is the most common endoscopic finding in Chinese patients with upper GI symptoms. Precancerous lesions, including atrophy, intestinal metaplasia and dysplasia are prevalent in Chinese patients with chronic gastritis, and endoscopic features are useful for predicting pathologic atrophy.

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Figures

Figure 1
Figure 1
Visual analog scale for histopathology assessment.
Figure 2
Figure 2
Most commonly prescribed medications for Chinese patients with chronic gastritis (n = 8892).
See this image and copyright information in PMC

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