Convergence of advances in genomics, team science, and repositories as drivers of progress in psychiatric genomics

Abstract

After many years of unfilled promise, psychiatric genetics has seen an unprecedented number of successes in recent years. We hypothesize that the field has reached an inflection point through a confluence of four key developments: advances in genomics; the orientation of the scientific community around large collaborative team science projects; the development of sample and data repositories; and a policy framework for sharing and accessing these resources. We discuss these domains and their effect on scientific progress and provide a perspective on why we think this is only the beginning of a new era in scientific discovery.

Keywords: Biosamples; Data Sharing; NIMH Repository and Genomics Resource; Psychiatric Genomics; Team Science; dbGaP.