How growth due to infant nutrition influences obesity and later disease risk
- PMID: 24521522
- DOI: 10.1111/apa.12593
How growth due to infant nutrition influences obesity and later disease risk
Abstract
Infant nutrition has a major impact on immediate outcomes and long-term health and later disease risks, such as obesity and related disorders, a phenomenon referred to as 'metabolic programming'. This review discusses the currently postulated hypotheses and mechanisms investigated by the EarlyNutrition project.
Conclusion: Rapid weight gain in the first 2 years of life, most notably mediated by diary protein, affects the insulin-like growth factor metabolic pathways. Epigenetic processes seem to play a role.
Keywords: Early nutrition; Growth; Infant nutrition; Metabolic programming; Obesity.
©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
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