On the neurolinguistic nature of language abnormalities in Huntington's disease
- PMID: 2452241
- PMCID: PMC1032862
- DOI: 10.1136/jnnp.51.3.367
On the neurolinguistic nature of language abnormalities in Huntington's disease
Abstract
Spontaneous language of 18 patients suffering from Huntington's disease and 15 dysarthric controls suffering from Friedreich's ataxia were investigated. In addition, language functions in various modalities were assessed with the Aachen Aphasia Test (AAT). The Huntington patients exhibited deficits in the syntactical complexity of spontaneous speech and in the Token Test, confrontation naming, and language comprehension subtests of the AAT, which are interpreted as resulting from their dementia. Errors affecting word access mechanisms and production of syntactical structures as such were not encountered.
Similar articles
-
Neurolinguistic features of spontaneous language production dissociate three forms of neurodegenerative disease: Alzheimer's, Huntington's, and Parkinson's.Brain Lang. 1989 Nov;37(4):628-42. doi: 10.1016/0093-934x(89)90116-8. Brain Lang. 1989. PMID: 2479447
-
Neurolinguistic characteristics of language production in Huntington's disease: a preliminary report.Brain Lang. 1987 May;31(1):1-10. doi: 10.1016/0093-934x(87)90056-3. Brain Lang. 1987. PMID: 2437992
-
Language functions in Huntington's disease.Brain. 1988 Dec;111 ( Pt 6):1475-503. doi: 10.1093/brain/111.6.1475. Brain. 1988. PMID: 2974745
-
[Huntington's disease: molecular foundations and implications in the characterisation of the neuronal mechanisms responsible for linguistic processing].Rev Neurol. 2009 Jan 16-31;48(2):75-84. Rev Neurol. 2009. PMID: 19173205 Review. Spanish.
-
[Saccadic eye movements in extrapyramidal disorders and particularly in Huntington's disease].Neurologia. 2001 Feb;16(2):57-62. Neurologia. 2001. PMID: 11257930 Review. Spanish. No abstract available.
Cited by
-
Hand muscle reflexes following electrical stimulation in choreatic movement disorders.J Neurol Neurosurg Psychiatry. 1989 Jun;52(6):755-62. doi: 10.1136/jnnp.52.6.755. J Neurol Neurosurg Psychiatry. 1989. PMID: 2526199 Free PMC article.
-
Early Language Impairment as an Integral Part of the Cognitive Phenotype in Huntington's Disease.Ann Clin Transl Neurol. 2025 Jun;12(6):1201-1213. doi: 10.1002/acn3.70022. Epub 2025 Apr 17. Ann Clin Transl Neurol. 2025. PMID: 40244831 Free PMC article.
-
A Practical Guide for Clinical Approach to Patients With Huntington's Disease in Korea.J Mov Disord. 2024 Apr;17(2):138-149. doi: 10.14802/jmd.24040. Epub 2024 Mar 12. J Mov Disord. 2024. PMID: 38467449 Free PMC article. No abstract available.
References
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Research Materials
Miscellaneous