Sorting the role of SORLA in Alzheimer's disease
- PMID: 24523319
- DOI: 10.1126/scitranslmed.3008562
Sorting the role of SORLA in Alzheimer's disease
Abstract
Cell culture and mouse models unravel how the SORLA receptor negatively regulates β-amyloid (Caglayan et al.).
Comment on
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Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation.Sci Transl Med. 2014 Feb 12;6(223):223ra20. doi: 10.1126/scitranslmed.3007747. Sci Transl Med. 2014. PMID: 24523320
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