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. 2014 Jan;11(1):19-21.
doi: 10.1038/nmeth.2783.

Dissecting genomic diversity, one cell at a time

Paul C Blainey, Stephen R Quake

Dissecting genomic diversity, one cell at a time

Paul C Blainey et al. Nat Methods. 2014 Jan.

Erratum in

  • Nat Methods. 2014 Mar;11(3):349

Abstract

Emerging technologies are bringing single-cell genome sequencing into the mainstream; this field has already yielded insights into the genetic architecture and variability between cells that highlight the dynamic nature of the genome.

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Figures

None
A single-cell genome image of polytene chromosomes from the 1882 monograph by Flemming (ref. 1).
See this image and copyright information in PMC

References

    1. Flemming W. Zellsubstanz, Kern und Zelltheilung. Vogel; 1882.
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    1. Hubert R, MacDonald M, Gusella J, Arnheim N. Nat. Genet. 1994;7:420–424. - PubMed
    1. Handyside AH, et al. N. Engl. J. Med. 1992;327:905–909. - PubMed
    1. Blainey PC. FEMS Microbiol. Rev. 2013;37:407–427. - PMC - PubMed