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. 2014 May-Jun;18(3):315-26.
doi: 10.1016/j.bjid.2014.01.002. Epub 2014 Feb 11.

Consensus of the Brazilian Society of Infectious Diseases and Brazilian Society of Clinical Oncology on the management and treatment of Kaposi's sarcoma

Érico Arruda  1 , Alexandre Andrade dos Anjos Jacome  2 , Ana Luiza de Castro Conde Toscano  3 , Anderson Arantes Silvestrini  4 , André Santa Bárbara Rêgo  5 , Evanius Garcia Wiermann  6 , Geraldo Felicio da Cunha Jr  7 , Heloisa Ramos Lacerda de Melo  8 , Karen Mirna Loro Morejón  9 , Luciano Zubaran Goldani  10 , Luiz Carlos Pereira Jr  11 , Mariliza Henrique Silva  12 , Mauro Sergio Treistman  13 , Mônica Cristina Toledo Pereira  14 , Patricia Maria Bezerra Xavier Romero  15 , Rafael Aron Schmerling  16 , Rodrigo Antonio Vieira Guedes  17 , Veridiana Pires de Camargo  18
Affiliations

Consensus of the Brazilian Society of Infectious Diseases and Brazilian Society of Clinical Oncology on the management and treatment of Kaposi's sarcoma

Érico Arruda et al. Braz J Infect Dis. 2014 May-Jun.

Erratum in

  • Braz J Infect Dis. 2014 Jul-Aug;18(4):468

Abstract

Kaposi's sarcoma is a multifocal vascular lesion of low-grade potential that is most often present in mucocutaneous sites and usually also affects lymph nodes and visceral organs. The condition may manifest through purplish lesions, flat or raised with an irregular shape, gastrointestinal bleeding due to lesions located in the digestive system, and dyspnea and hemoptysis associated with pulmonary lesions. In the early 1980s, the appearance of several cases of Kaposi's sarcoma in homosexual men was the first alarm about a newly identified epidemic, acquired immunodeficiency syndrome. In 1994, it was finally demonstrated that the presence of a herpes virus associated with Kaposi's sarcoma called HHV-8 or Kaposi's sarcoma herpes virus and its genetic sequence was rapidly deciphered. The prevalence of this virus is very high (about 50%) in some African populations, but stands between 2% and 8% for the entire world population. Kaposi's sarcoma only develops when the immune system is depressed, as in acquired immunodeficiency syndrome, which appears to be associated with a specific variant of the Kaposi's sarcoma herpes virus. There are no treatment guidelines for Kaposi's sarcoma established in Brazil, and thus the Brazilian Society of Clinical Oncology and the Brazilian Society of Infectious Diseases developed the treatment consensus presented here.

Keywords: AIDS; Consensus; Cutaneous; Kaposi's sarcoma.

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Figures

Fig. 1
Fig. 1
Incidence of Kaposi's sarcoma – Brazil 1980 to June/2012.
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