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. 2014 Jan 16:6:1-4.
doi: 10.4137/OED.S13102. eCollection 2014.

Cohort study of intracameral moxifloxacin in postoperative endophthalmitis prophylaxis

Virgilio Galvis  1 , Alejandro Tello  1 , Mary Alejandra Sánchez  2 , Paul Anthony Camacho  2
Affiliations

Cohort study of intracameral moxifloxacin in postoperative endophthalmitis prophylaxis

Virgilio Galvis et al. Ophthalmol Eye Dis. .

Abstract

We conducted a cohort study to evaluate post-cataract surgery endophthalmitis rates in relation to prophylactic intracameral moxifloxacin administration. A total of 2332 patients (2674 eyes) who underwent phacoemulsification by a single surgeon from January 2007 through December 2012 were included in the study. A total of 1056 eyes did not receive intracameral prophylactic moxifloxacin and the antibiotic was injected in 1618 eyes. The incidence of presumed postoperative endophthalmitis in the 2 groups was calculated. The rate of presumed infectious endophthalmitis after cataract surgery between January 2007 and June 2009 (without intracameral moxifloxacin) was 0.094%. The rate in the second period, from July 2009 to December 2012 (with prophylactic intracameral moxifloxacin), was 0%. In our patients, a decline in the incidence of presumed infectious postoperative endophthalmitis appeared to be associated with the application of intracameral moxifloxacin.

Keywords: cataract surgery; endophthalmitis; intracameral antibiotics.

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