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. 2014 Mar;7(3):894-896.
doi: 10.3892/ol.2014.1812. Epub 2014 Jan 17.

Huge giant cell tumor of the sacrum: A case report

Li-Feng Qin  1 , Dan Peng  1 , Li-Hua Qin  2 , Min Xu  3 , Han Fang  4 , Qing Zhang  1
Affiliations

Huge giant cell tumor of the sacrum: A case report

Li-Feng Qin et al. Oncol Lett. 2014 Mar.

Abstract

The current report describes the case of a 29-year-old female with a sacral giant cell tumor (GCT) during pregnancy. Originally, the patient presented with severe pain in the lumbosacral region, radiating posterolaterally from the lumbar spine into the bilateral thigh and subsequently, into the bilateral crus posterolaterally. Plain X-rays, computed tomography and magnetic resonance imaging showed osteolytic destruction of the sacrococcygeal bones and a huge soft-tissue mass with features of a chordoma. The patient underwent a partial en bloc sacrectomy (partial S1 and completely below) and curettage for tumors located at the sacroiliac joint and underlying left ilium, with bilateral internal iliac arteries ligated to control intraoperative hemorrhage. The patient's bilateral S2 nerve roots were killed. The diagnosis of conventional GCT was determined based on the histopathological examination of the resected specimen. Urinary and bowel functions were recovered by exercising.

Keywords: S2 nerve root; chordoma; giant cell tumor; rectum; sacral tumor; urinary and bowel function.

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Figures

Figure 1
Figure 1
(A) Computed tomography (CT) scan and (B and C) three-dimensional reconstruction showing osteolytic destruction of the sacrum and a large soft-tissue mass involving the underlying left ilium. (B) Three-dimensional scan viewed from the front. (C) Three-dimensional scan viewed from behind. The sacral canal was enlarged and the left medial ilium (near sacroiliac joints) was destroyed.
Figure 2
Figure 2
(A and B) Magnetic resonance images (MRI) showing the destruction of the sacrococcygeal bones and a huge soft-tissue mass. On T1- and T2-weighted images, the lesion showed large patches of mixed signal shadows, which followed the plane of the first sacral vertebra. (A) The boundary between the mass and the rectum was unclear. (B) Upon enhanced scanning, the lesions appeared more pronounced.
Figure 3
Figure 3
Plain X-ray of the (A) pelvic and (B) sacroiliac regions six months after surgery, neither of which exhibited any looseness or fractures of internal fixation or new bone destruction.
See this image and copyright information in PMC

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