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Review
. 2012 Jun 23;3(4):77-81.
doi: 10.1016/j.jcws.2012.06.001. eCollection 2011 Dec.

Drug-hypersensitivity syndrome: diagnosis and treatment

Rose L Hamm  1
Affiliations
Review

Drug-hypersensitivity syndrome: diagnosis and treatment

Rose L Hamm. J Am Coll Clin Wound Spec. .

Abstract

Drug-induced hypersensitivity syndrome is a systemic autoimmune disorder that results in mucocutaneous symptoms ranging in severity from mild pruritus to life-threatening skin and mucosal loss, with different nomenclature depending on the severity of the symptoms. The purpose of this article is to review the recent advances in understanding the pathology of drug-induced hypersensitivity syndrome, as well as current recommendations for both medical and wound management.

Keywords: DRESS syndrome; Drug-induced hypersensitivity syndrome; Erythema multiform; Stevens-Johnson syndrome; Toxic epidermal necrolysis.

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Figures

Figure 1
Figure 1
Skin Lesions on the Leg of a Patient With Toxic Epidermal Necrosis.
Figure 2
Figure 2
Oral Lesions and Epidermal Necrolysis Visible on a Patient With Toxic Epidermal Necrosis.
See this image and copyright information in PMC

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