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Review
. 2014 Jan;3(1):1-8.
doi: 10.7762/cnr.2014.3.1.1. Epub 2014 Jan 27.

Nutrition, epigenetics, and diseases

Hyeran Jang  1 , Carlo Serra  1
Affiliations
Review

Nutrition, epigenetics, and diseases

Hyeran Jang et al. Clin Nutr Res. 2014 Jan.

Abstract

Increasing epidemiological evidence suggests that maternal nutrition and environmental exposure early in development play an important role in susceptibility to disease in later life. In addition, these disease outcomes seem to pass through subsequent generations. Epigenetic modifications provide a potential link between the nutrition status during critical periods in development and changes in gene expression that may lead to disease phenotypes. An increasing body of evidence from experimental animal studies supports the role of epigenetics in disease susceptibility during critical developmental periods, including periconceptional period, gestation, and early postnatal period. The rapid improvements in genetic and epigenetic technologies will allow comprehensive investigations of the relevance of these epigenetic phenomena in human diseases.

Keywords: Development; Disease; Epigenetic; Nutrition; Reprogramming.

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Conflict of interest statement

We declare that we have no conflict of interest.

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