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Review
. 2014:2014:608979.
doi: 10.1155/2014/608979. Epub 2014 Jan 2.

Food-derived bioactive peptides on inflammation and oxidative stress

Subhadeep Chakrabarti  1 , Forough Jahandideh  1 , Jianping Wu  1
Affiliations
Review

Food-derived bioactive peptides on inflammation and oxidative stress

Subhadeep Chakrabarti et al. Biomed Res Int. 2014.

Abstract

Chronic diseases such as atherosclerosis and cancer are now the leading causes of morbidity and mortality worldwide. Inflammatory processes and oxidative stress underlie the pathogenesis of these pathological conditions. Bioactive peptides derived from food proteins have been evaluated for various beneficial effects, including anti-inflammatory and antioxidant properties. In this review, we summarize the roles of various food-derived bioactive peptides in inflammation and oxidative stress and discuss the potential benefits and limitations of using these compounds against the burden of chronic diseases.

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Figures

Figure 1
Figure 1
The potential mechanisms of action of anti-inflammatory bioactive peptides and peptide-rich protein hydrolysates. MAPK: mitogen activated protein kinase; NF-κB: nuclear factor-κB; COX-2: cyclo-oxygenase-2; TGF-beta: transforming growth factor-beta; IL-10: interleukin-10; RAS: renin-angiotensin system; ROS: reactive oxygen species.
See this image and copyright information in PMC

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