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Comment
. 2014 Feb 12;15(2):130-1.
doi: 10.1016/j.chom.2014.01.014.

Influenza A virus lures autophagic protein LC3 to budding sites

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Influenza A virus lures autophagic protein LC3 to budding sites

Christian Münz. Cell Host Microbe. .
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Abstract

Autophagy, a cellular degradation pathway, can restrict or assist viral replication. In this issue of Cell Host & Microbe, Beale et al. (2014) report that the influenza virus matrix protein 2 binds to the essential autophagy protein LC3 to presumably transport LC3-conjugated membranes to the cell surface for budding of stable viruses.

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