Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2014 Apr 7;32(17):1901-20.
doi: 10.1016/j.vaccine.2014.01.091. Epub 2014 Feb 14.

Educational interventions to increase HPV vaccination acceptance: a systematic review

Linda Y Fu  1 , Lize-Anne Bonhomme  2 , Spring Chenoa Cooper  3 , Jill G Joseph  4 , Gregory D Zimet  5
Affiliations
Comparative Study

Educational interventions to increase HPV vaccination acceptance: a systematic review

Linda Y Fu et al. Vaccine. .

Abstract

Background: The Human papillomavirus (HPV) vaccine has been available for protection against HPV-associated cervical cancer and genital warts since 2006. Nonetheless, uptake has varied among countries and populations within countries. Studies have found that individuals' knowledge and attitudes toward the vaccine are associated with immunization uptake. The purpose of the current review is to summarize and evaluate the evidence for educational interventions to increase HPV vaccination acceptance.

Methods: We searched the databases of PubMed and Web of Science for English-language articles describing educational interventions designed to improve HPV vaccination uptake, intention or attitude.

Results: We identified 33 studies of HPV vaccination educational interventions: 7 tested the effectiveness of interventions with parents, 8 with adolescents or young adults, and 18 compared the effectiveness of different message frames in an educational intervention among adolescents, young adults or their parents. Most studies involved populations with higher educational attainment and most interventions required participants to be literate. The minority of studies used the outcome of HPV vaccine uptake. Well-designed studies adequately powered to detect change in vaccine uptake were rare and generally did not demonstrate effectiveness of the tested intervention.

Conclusions: There is not strong evidence to recommend any specific educational intervention for wide-spread implementation. Future studies are required to determine the effectiveness of culturally-competent interventions reaching diverse populations.

Keywords: Attitude to health; Decision making; Education; Intervention studies; Papillomavirus vaccines; Systematic review.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Flow chart of included and excluded studies.
See this image and copyright information in PMC

Comment in

References

    1. Forman D, de Martel C, Lacey C. Global burden of human papillomavirus and related diseases. Vaccine. 2012;30:F12–23. - PubMed
    1. Schwarz TF. AS04-adjuvanted human papillomavirus-16/18 vaccination: recent advances in cervical cancer prevention. Expert Rev Vaccines. 2008;7(10):1465–73. - PubMed
    1. Munoz N, Bosch FX, Castellsague X, et al. Against which human papillomavirus types shall we vaccinate and screen? The international perspective. Int J Cancer. 2004;111(2):278–85. - PubMed
    1. Bryan JT. Developing an HPV vaccine to prevent cervical cancer and genital warts. Vaccine. 2007;25(16):3001–6. - PubMed
    1. Gorin SNS, Glenn BA, Perkins RB. The human papillomavirus (HPV) vaccine and cervical cancer: uptake and next steps. Adv Ther. 2011;28(8):615–39. - PubMed

Publication types

Substances