[Effect of the average diet of the State of São Paulo, from time of pregnancy on body weight and composition of the offspring. Study in rats]

Abstract

The effect of diet of São Paulo State on some biochemical parameters in the liver, brain and plasma of rats at weaning and 90 days was studied. The tissue parameters studied were the amounts of DNA, RNA and protein in the liver and brain. For the plasma were the total protein and albumin. Wistar rat were fed a 13% casein (control) and 13% protein of experimental diet since the gestation. In experimental diet weight at birth, weaning and 90 days were considerably reduced. A comparison of the data of the experimental rats in relation to the control group indicated that: a) organ weight, total organ DNA, RNA and protein were all reduced; b) no differences in total protein and albumin in plasma were observed between the control and the experimental group. These results suggest that the diet experimental is deficient in some nutrients (minerals, vitamins?) and affected the cellular development of brain and liver.