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. 2014 Feb 17;15(1):20.
doi: 10.1186/1465-9921-15-20.

Impact of gender on COPD expression in a real-life cohort

Nicolas Roche  1 , Gaetan Deslée, Denis Caillaud, Graziella Brinchault, Isabelle Court-Fortune, Pascale Nesme-Meyer, Pascale Surpas, Roger Escamilla, Thierry Perez, Pascal Chanez, Christophe Pinet, Gilles Jebrak, Jean-Louis Paillasseur, Pierre-Régis Burgel; INITIATIVES BPCO Scientific Committee
Affiliations

Impact of gender on COPD expression in a real-life cohort

Nicolas Roche et al. Respir Res. .

Abstract

Reports regarding gender-related differences in COPD expression have provided conflicting results. In the French Initiatives BPCO real-world cohort, which contained 688 patients (146 women) when data were extracted, women were matched with men (1:3 ratio: n = 107:275) on age (5-year intervals) and FEV1 (5% predicted intervals) and comparisons were performed using univariate logistic regressions. For a given age and level of airflow obstruction, women with COPD had higher BOD scores due to more pronounced dyspnea and lower BMI, suggesting worse prognosis, and were more likely to exhibit anxiety, suggesting the need for specific assessment and care.

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