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Review
. 2014 Jun;147(6):1749-57, 1757.e1.
doi: 10.1016/j.jtcvs.2014.01.021. Epub 2014 Jan 21.

Surgical treatment of bicuspid aortic valve disease: knowledge gaps and research perspectives

Alessandro Della Corte  1 , Simon C Body  2 , Anna M Booher  3 , Hans-Joachim Schaefers  4 , Rita K Milewski  5 , Hector I Michelena  6 , Arturo Evangelista  7 , Philippe Pibarot  8 , Patrick Mathieu  8 , Giuseppe Limongelli  9 , Prem S Shekar  10 , Sary F Aranki  10 , Andrea Ballotta  11 , Giuseppe Di Benedetto  12 , Natzi Sakalihasan  13 , Gianantonio Nappi  14 , Kim A Eagle  3 , Joseph E Bavaria  5 , Alessandro Frigiola  11 , Thoralf M Sundt  15 ; International Bicuspid Aortic Valve Consortium (BAVCon) Investigators
Collaborators, Affiliations
Review

Surgical treatment of bicuspid aortic valve disease: knowledge gaps and research perspectives

Alessandro Della Corte et al. J Thorac Cardiovasc Surg. 2014 Jun.
No abstract available

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Figures

Figure 1
Figure 1
The research approach to BAV aortopathy: past and future. Up to a few years ago, research on BAV aortopathy interpreted clinical aspects (eg, rate of progression, relation with severity of valve dysfunction, risk of dissection) with the aim of drawing inferences on the pathogenesis, that is, alternatively supporting the hemodynamic or the genetic theory. Inconclusive results and increasing awareness of the phenotypic heterogeneity have led to an inversely oriented approach: the contribution of either pathogenetic factor is investigated to identify the respective potential prognostic value in the clinical setting. AVR, Aortic valve replacement; BAV, bicuspid aortic valve.
Figure 2
Figure 2
Borderline conditions. Intraoperative photographs from a patient with dilated ascending aorta (left: 50 mm at the midascending tract bulging toward the right and anteriorly, 35 mm at the sinotubular junction, 38 mm at sinuses, and normal distal ascending and arch diameters) and BAV (right: fusion of the right and left coronary leaflets, partial fibrous noncalcific raphe, a nearly 180° position of the commissures, no stenosis, and trivial regurgitation at echocardiography). According to published series, different investigators would treat this unique condition by a variety of techniques, including simple ascending replacement, ascending reduction aortoplasty, ascending and root replacement with valve sparing, Wheat operation, Bentall operation, and so forth.
See this image and copyright information in PMC

References

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