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. 1988 Mar;101(3):129-31.
doi: 10.1007/BF00437029.

Histopathology of experimental Aspergillus fumigatus keratitis

A Fons  1 , J García-de-Lomas, J M Nogueira, F J Buesa, C Gimeno
Affiliations

Histopathology of experimental Aspergillus fumigatus keratitis

A Fons et al. Mycopathologia. 1988 Mar.

Abstract

Histopathological studies in rabbit's eyes, 7 and 14 days after intracorneal inoculation with 1 X 10(5) Aspergillus fumigatus conidia have been performed. Similar lesions were found in both periods with fungal hyphae in the anterior third of corneal stroma, round cell infiltration from the sclero-corneal edge and in the anterior chamber and, neovascularization. No lesions were found in the Descemet's membrane. Gomori silver-methenamine stain with hematoxiline-eosine counter-stain was found to be the most reliable stain to detect fungal presence in corneal stroma, and Masson's trichromic stain in the study of pathological changes in ocular elements.

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