[Interaction of anemone toxin BgTX8 with the ion channels of isolated mammalian neurons]
[Article in
Russian]
- PMID: 2454410
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[Interaction of anemone toxin BgTX8 with the ion channels of isolated mammalian neurons]
[Article in
Russian]
Neirofiziologiia.
1988.
Abstract
Interaction between anemone toxin BgTX8 and sodium channels in isolated single neurons of rat sensory ganglia was studied by voltage-clamp and intracellular perfusion techniques. It was shown that BgTX8 in external and internal solutions induced a dose-dependent slowdown of inactivation kinetics. Dissociation constant for receptor-toxin complex was found to be 4.10(-6) mol/l.
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