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. 1988 Mar 22;233(1271):191-9.
doi: 10.1098/rspb.1988.0018.

A calcium-independent chloride current activated by hyperpolarization in Xenopus oocytes

I Parker  1 , R Miledi
Affiliations

A calcium-independent chloride current activated by hyperpolarization in Xenopus oocytes

I Parker et al. Proc R Soc Lond B Biol Sci. .

Abstract

Hyperpolarization of oocytes of Xenopus laevis usually elicits mainly passive currents. However, when polarized to potentials more negative than about -100 mV, oocytes obtained from some donors show a relatively well maintained current that is carried mainly by chloride ions. This response does not depend upon external calcium, and is thus clearly different from the calcium-dependent transient chloride current previously described.

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