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. 2014 Nov;55(11):2584-91.
doi: 10.3109/10428194.2014.894189. Epub 2014 Mar 31.

Acute myeloid leukemia risk by industry and occupation

Rebecca J Tsai  1 , Sara E Luckhaupt, Pam Schumacher, Rosemary D Cress, Dennis M Deapen, Geoffrey M Calvert
Affiliations

Acute myeloid leukemia risk by industry and occupation

Rebecca J Tsai et al. Leuk Lymphoma. 2014 Nov.

Abstract

Acute myeloid leukemia (AML) is the most common type of leukemia found in adults. Identifying jobs that pose a risk for AML may be useful for identifying new risk factors. A matched case-control analysis was conducted using California Cancer Registry data from 1988 to 2007. This study included 8999 cases of AML and 24 822 controls. Industries with a statistically significant increased AML risk were construction (matched odds ratio [mOR] = 1.13); crop production (mOR = 1.41); support activities for agriculture and forestry (mOR = 2.05); and animal slaughtering and processing (mOR = 2.09). Among occupations with a statistically significant increased AML risk were miscellaneous agricultural workers (mOR = 1.76); fishers and related fishing workers (mOR = 2.02); nursing, psychiatric and home health aides (mOR = 1.65); and janitors and building cleaners (mOR = 1.54). Further investigation is needed to confirm study findings and to identify specific exposures responsible for the increased risks.

Keywords: Acute myeloid leukemia; industry; occupation; risk factors.

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